Reproductive Hazards
Reproductive toxins are defined by the OSHA Laboratory Standard as substances that cause chromosomal damage (mutagens) and/or substances with lethal or teratogenic (malformation) effects on fetuses. These can include chemicals, biologicals, and radioactive materials. Chapter 8 of the UNC Lab Safety Manual outlines the proper precautions, postings, procedures and controls when working with reproductive hazards.
Examples of reproductive toxins commonly found in laboratories include:
Arsenic
Benzene
Cadmium
Carbon disulfide
Dibromochoropropane
Ethylene dibromide
Ethylene glycol monomethyl (and ethyl) ethers
Ethylene oxide
Fluorouracil (5-FU)
Ionizing radiation
Lead
Mercury compounds
Polychlorinated biphenols (PCBs)
Tamoxifen
Toluene
Urethane
UNC is committed to providing additional protection for the conceptus, and to establish specific procedures to protect pregnant employees. Review Chapter 8 of the UNC Lab Safety Manual for more information regarding the University's Conceptus Protection Program. If you wish to take advantage of the program, contact EHS as soon as possible after determining or contemplating pregnancy.
Fact Sheets:
- CDC – Radiation and Pregnancy
- NIOSH – The Effects of Workplace Hazards on Female Reproductive Health
- NIOSH – The Effects of Workplace Hazards on Male Reproductive Health
Other Resources:
- California Prop 65: Chemicals Known to the State to Cause Cancer or Reproductive Toxicity (July 2011)
- NIOSH Workplace Safety & Health Topics: Reproductive Health
- OSHA Safety and Health Topic: Reproductive Hazards

